| 货号 | 3891S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IHC-P |
| 目标/特异性 | Phospho-Glycogen Synthase (Ser641) Antibody detects endogenous levels of both muscle and liver isoforms of glycogen synthase only when phosphorylated at serine 640 or 641 of the muscle and liver isoforms, respectively. |
| 使用方法 | WB(1:1000) IP (1:100) IHC-P (1:50) |
| 供应商 | CST |
| 背景 | Glycogen synthase (GS) is a key enzyme in the regulation of glycogen synthesis. There are two main isoforms of mammalian GS: the muscle and the liver isoform (1-2). Muscle GS is expressed in several tissues, and liver GS appears to be tissue specific (3). GS is regulated by multi-site phosphorylation and by the binding of allosteric ligands. Phosphorylation leads to inactivation of GS, but activity is restored by the binding of the allosteric activator glucose-6-phosphate, which induces its dephosphorylation and activation (4). |
| 存放说明 | -20C |
| 计算分子量 | 85 to 90 |
Western blot analysis of extracts from NIH/3T3 cells treated with calf intestinal alkaline phosphatase (CIP), using Phospho-Glycogen Synthase (Ser641) Antibody (upper) or control glycogen synthase antibody (lower). Wetern blot检测NIH/3T3细胞提取物，细胞用calf intestinal alkaline phosphatase (CIP)处理，所用抗体为Phospho-Glycogen Synthase (Ser641) Antibody (上)和control glycogen synthase antibody (下)。 | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma, showing cytoplasmic localization, using Phospho-Glycogen Synthase (Ser641) Antibody. 免疫组织化学检测石蜡包埋的人乳腺癌组织，所用抗体为Phospho-Glycogen Synthase (Ser641) Antibody，显示胞质定位 | |
Immunohistochemical analysis of paraffin-embedded renal clear cell adenocarcinoma using Phospho-Glycogen Synthase (Ser641) Antibody. 免疫组织化学检测石蜡包埋的人肾透明细胞腺瘤组织，所用抗体为Phospho-Glycogen Synthase (Ser641) Antibody |
