Phospho-Etk (Tyr40) Antibody
货号：
3211S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 3211S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | Phospho-Etk (Tyr40) Antibody detects endogenous levels of Etk only when phosphorylated at Tyr40. This antibody may cross react with activated EGF Receptor. This antibody may cross react with other family members including ITK and BTK when overexpressed. |
| 使用方法 | WB(1:1000)
IP (1:50) |
性能| 供应商 | CST |
| 背景 | Etk, also known as BMX, is a member of the Brutons tyrosine kinase (Btk) family (1). It is expressed in a variety of hematopoietic, epithelial and endothelial cells. Etk, like other Btk family members, contains a pleckstrin homology (PH) domain and Src homology SH3 and SH2 domains. It participates in multiple signal transduction pathways (2). Phosphorylation of Tyr566 by Src kinase is required for activation of Etk in vivo (3). In endothelial and epithelial cells, Etk is regulated by FAK through phosphorylation at Tyr40 (4). |
| 存放说明 | -20C |
| 计算分子量 | 76 |
参考图片Western blot analysis of extracts from Jurkat cells, untreated or anti-CD3 antibody-treated, using Phospho-Etk (Tyr40) Antibody (upper) or Etk Antibody #3212 (lower).用抗磷酸化Etk (Tyr40)的抗体（上）或抗Etk 的抗体 #3212（下）对经过或未经抗CD3抗体预处理的Jurkat细胞进行免疫印迹检测。 |
