Phospho-DR6 (Ser562) Antibody
货号：
7616S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 7616S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Phospho-DR6 (Ser562) Antibody recognizes endogenous levels of DR6 protein only when phosphorylated at Ser562. This antibody may recognize DR6 with dual phosphorylation at Ser562 and Ser565. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems (1,2). The receptors are activated by a family of cytokines that include TNF, FasL, and TRAIL. They are characterized by a highly conserved extracellular region containing cysteine-rich repeats and a conserved intracellular region of about 80 amino acids termed the death domain (DD). The DD is important for transducing the death signal by recruiting other DD containing adaptor proteins (FADD, TRADD, RIP) to the death-inducing signaling complex (DISC), resulting in activation of caspases. |
| 存放说明 | -20C |
| 计算分子量 | 80 |
参考图片Western blot analysis of extracts from serum-starved A-431 cells, untreated (-) or treated with Human Epidermal Growth Factor (hEGF) #8916 (100 ng/ml, 30 min) (+) using Phospho-DR6 (Ser562) Antibody (top) or α-Tubulin (11H10) Rabbit mAb #2125 (bottom). 免疫印迹分析血清饥饿的A-431细胞的提取物，未处理 (-)或Human Epidermal Growth Factor (hEGF) #8916 (100 ng/ml, 30 min) (+)处理，使用抗体为Phospho-DR6 (Ser562) Antibody（上图）或 α-Tubulin (11H10) Rabbit mAb 兔单抗#2125（下图）。 |
