Phospho-DDR1 (Tyr792) Antibody
货号：
11994S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 11994S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | Phospho-DDR1 (Tyr792) Antibody recognizes endogenous levels of DDR1 protein only when phosphorylated at Tyr792. This antibody may cross-reacts with other tyrosine-phosphorylated RTKs. |
| 使用方法 | WB(1:1000)
IP (1:100) |
性能| 供应商 | CST |
| 背景 | The discoidin domain receptors (DDRs) are receptor tyrosine kinases with a discoidin homology repeat in their extracellular domains, activated by binding to extracellular matrix collagens. So far, two mammalian DDRs have been identified: DDR1 and DDR2 (1). They are widely expressed in human tissues and may have roles in smooth muscle cell-mediated collagen remodeling (2). Research studies have implicated aberrant expression and signaling of DDRs in human diseases related to increased matrix degradation and remodeling, such as cardiovascular disease, liver fibrosis, and tumor invasion (1). |
| 存放说明 | -20C |
| 计算分子量 | 125 |
参考图片Western blot analysis of extracts from T-47D cells, untreated (-) or treated with collagen (15 μg/ml) for the indicated times, using Phospho-DDR1 (Tyr792) Antibody (upper) or DDR1 (D1G6) XP® Rabbit mAb #5583 (lower).Western blot方法检测T-47D细胞提取物，细胞不处理（-）或用胶原蛋白（15 μg/ml）处理指定的时间，使用的抗体为Phospho-DDR1 (Tyr792) Antibody (上图)或DDR1 (D1G6) XP® Rabbit mAb #5583 (下图). |
