Phospho-C/EBPbeta (Ser105) Antibody (Rat Specific)
货号：
3081S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 3081S |
| 反应种属 | Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Phospho-C/EBPbeta (Ser105) Antibody (Rat Specific) detects endogenous levels of rat C/EBPbeta only when phosphorylated at serine 105. It does not cross-react with phosphorylated rat C/EBP family members alpha, delta, gamma, epsilon or zeta. It also does not recognize the p20 LIP rat C/EBPbeta isoform. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | CCAAT/enhancer-binding proteins (C/EBPs) are a family of transcription factors critical for cellular differentiation, terminal functions and inflammatory response (1). Six members of the family have been characterized (C/EBPα, -β, -γ, -δ, -ε and -ζ) and are distributed in a variety of tissues (1). There are two forms of C/EBPβ, the 38 kDa liver activating protein (LAP) and the 20 kDa liver inhibitory protein (LIP) which may be products of alternative translation. The 38 kDa LAP protein is a transcriptional activator while LIP may act as an inhibitor of C/EBPβ transcriptional activity (2). Phosphorylation of C/EBPβ at distinct sites stimulates its transcriptional activity (3-5). Phosphorylation at serine 105 of rat C/EBPβ, a unique site only present in the rat sequence, seems essential for rat C/EBPβ activation (6). |
| 存放说明 | -20C |
| 计算分子量 | 41 |
参考图片Western blot analysis of extracts from untreated or serum stimulated PC12 cells, using Phospho-C/EBPbeta (Ser105) Antibody (Rat Specific) (A, B) or C/EBPbeta Antibody #3082 (C, D). Nitrocellulose membranes B and D were treated with alkaline phosphatase (CIP) to show the phospho-specificity of Phospho-C/EBPbeta (Ser105) Antibody. 对PC12细胞抽提液（未处理或血清刺激），使用Phospho-C/EBPbeta (Ser105) Antibody (兔特异性) (A, B)或C/EBPbeta Antibody #3082 (C, D)进行Western blot分析。硝酸纤维素膜B和D经过碱性磷酸酶（CIP）处理以显示Phospho-C/EBPbeta (Ser105) Antibody的特异性。 |
