Cleaved Lamin A (Asp230) Antibody
货号：
2031S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 2031S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Cleaved Lamin A (Asp230) Antibody detects endogenous levels of the large fragment of lamin A (and lamin C isotype) resulting from cleavage at aspartic acid 230. The antibody does not recognize full length lamin A. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3,4). The cleavage of lamins results in nuclear disregulation and cell death (5,6). |
| 存放说明 | -20C |
| 计算分子量 | 45, 50 |
参考图片Western blot analysis of extracts from HeLa cells, untreated or staurosporine-treated (1 µM), using Cleaved Lamin A (Asp230) Antibody (upper) or Lamin A Antibody #2032 (lower). Western blot检测HeLa细胞提取物，未处理或staurosporine(星形孢菌素)(1 µM)处理，使用抗体为Cleaved Lamin A (Asp230) Antibody （上图）或Lamin A Antibody #2032 （下图）。 |
