Cleaved Drosophila ICE (drICE) (Asp230) Antibody
货号：
9478S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 9478S |
| 反应种属 | D.melanogaster |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Cell death in the fruit fly Drosophila melanogaster is regulated by many of the same stimuli as mammalian cell death (1). The Drosophila genome contains seven caspase genes; three encode initiator caspases and four encode effector caspases (reviewed in 2). drICE is a cysteine protease that cleaves baculovirus p35 and lamin DmO in vitro and acts downstream of rpr (3). drICE is proteolytically processed during apoptosis into active p21 and p12 subunits. Comparison of the in vivo activity between drICE and Dcp-1 has shown that drICE is a more effective inducer of apoptosis than Dcp-1, which plays a role in determining the rate of cell death (4). |
| 存放说明 | -20C |
| 计算分子量 | 21 |
参考图片Western blot analysis of extracts from Drosophila S2 cells, untreated (-) or treated with either cycloheximide (10 μM, 5 hr; +) or actinomycin D (0.7 μM, 5 hr; +), using Cleaved Drosophila ICE (drICE) (Asp230) Antibody. Western blot 检测果蝇S2细胞提取物，未处理 (-)或cycloheximide(放线菌酮) (10 μM, 5 hr; +) 或actinomycin(放线菌素D)(0.7 μM, 5 hr; +)处理，使用抗体为 Cleaved Drosophila ICE (drICE) (Asp230) Antibody。 |
