Acetyl-β-Catenin (Lys49) Antibody
货号：
9534S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 9534S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Acetyl-β-Catenin (Lys49) Antibody detects endogenous β-catenin only when acetylated at Lys49. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | β-Catenin is a key downstream effector in the Wnt signaling pathway (1). It is implicated in two major biological processes in vertebrates: early embryonic development (2) and tumorigenesis (3). CK1 phosphorylates β-catenin at Ser45. This phosphorylation event primes β-catenin for subsequent phosphorylation by GSK-3β (4-6). GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41 (7). Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines (8). |
| 存放说明 | -20C |
| 计算分子量 | 92 |
参考图片Western blot analysis of total cell lysates from 293 cells, untransfected or transiently transfected with a construct expressing CBP, using Acetyl-β-Catenin (Lys49) Antibody (Top), or total β-Catenin Antibody (Amino-terminal Antigen) #9581 (Bottom). 使用Acetyl-β-Catenin (Lys49) 抗体 (上),或 total β-Catenin抗体(氨基末端抗原) #9581 (底)对未转染或瞬转CBP表达质粒的293细胞提取物进行western blot实验。 |
