α-Smooth Muscle Actin Antibody
货号:
14968S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 14968S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | α-Smooth Muscle Actin Antibody recognizes endogenous levels of total α-smooth muscle actin protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
灵敏度 | Endogenous |
背景 | Actin proteins are major components of the eukaryotic cytoskeleton. At least six vertebrate actin isoforms have been identified. The cytoplasmic β- and γ-actin proteins are referred to as “non-muscle” actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility (1). The α-cardiac and α-skeletal actin proteins are expressed in striated cardiac and skeletal muscles, respectively. The smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is also known as aortic smooth muscle actin. These actin isoforms regulate the contractile potential of muscle cells (1). |
存放说明 | -20C |
计算分子量 | 42 |
参考文献 | 1 . Herman, I.M. (1993) Curr Opin Cell Biol 5, 48-55.
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参考图片Western blot analysis of extracts from various tissue using α-Smooth Muscle Actin Antibody (upper) and GAPDH (D16H11) XP® Rabbit mAb #5174 (lower). As expected, α-skeletal muscle extracts are negative for smooth muscle actin. |