| 货号 | 2064S |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | WIF1 Antibody detects transfected levels of total WIF1 protein. |
| 使用方法 | WB(1:1000) |
| 供应商 | CST |
| 灵敏度 | Transfected Only |
| 背景 | WIF1 (Wnt inhibitory factor 1) is a secreted protein that binds to Wnt proteins and inhibits their activity (1). It contains an N-terminal WIF domain and five EGF-like repeats (2). The WIF1 ortholog in Drosophila, Shifted, is required for Hedgehog stability and diffusion (3,4). It has been reported that WIF1 expression is downregulated in many types of cancers (5-8). |
| 存放说明 | -20C |
| 计算分子量 | 42 |
| 参考文献 | 1 . Hsieh, J.C. et al. (1999) Nature 398, 431-6. 2 . Liepinsh, E. et al. (2006) J Mol Biol 357, 942-50. 3 . Gorfinkiel, N. et al. (2005) Dev Cell 8, 241-53. 4 . Glise, B. et al. (2005) Dev Cell 8, 255-66. 5 . Wissmann, C. et al. (2003) J Pathol 201, 204-12. 6 . Taniguchi, H. et al. (2005) Oncogene 24, 7946-52. 7 . Mazieres, J. et al. (2004) Cancer Res 64, 4717-20. 8 . Mazieres, J. et al. (2005) Cancer Lett 222, 1-10. |
Western blot analysis of extracts from COS cells, mock transfected or transfected with a mouse WIF1 construct, using WIF1 Antibody. 使用WIF1抗体对未转染或转染了小鼠WIF1表达载体的COS细胞提取物进行western blot分析。 |
