货号 | 5214S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | TBX21 (V365) Antibody detects endogenous levels of total TBX21 protein. |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
灵敏度 | Endogenous |
背景 | The T-box gene family consists of transcription factors characterized by a related DNA-binding domain (T-box) of approximately 200 amino acids (1,2). The T-box genes exhibit diverse temporal and spatial patterns in the developing embryo. Studies have demonstrated members of this family play crucial roles during embryogenesis in a wide range of organisms by regulating cell fate decisions to establish the early body plan and to regulate later processes underlying organogenesis (3-5). Mutations in T-box genes are associated with many developmental defects (6). Recent studies also indicate potential roles in cancer by members of T-box family (7-9). |
存放说明 | -20C |
计算分子量 | 65 |
参考文献 | 1 . Wilkinson, D.G. et al. (1990) Nature 343, 657-9. 2 . Papaioannou, V.E. and Silver, L.M. (1998) Bioessays 20, 9-19. 3 . Showell, C. et al. (2004) Dev Dyn 229, 201-18. 4 . Papaioannou, V.E. (2001) Int Rev Cytol 207, 1-70. 5 . Hoogaars, W.M. et al. (2007) Cell Mol Life Sci 64, 646-60. 6 . Baldini, A. (2004) Curr Opin Cardiol 19, 201-4. 7 . Abrahams, A. et al. (2010) IUBMB Life 62, 92-102. 8 . Rowley, M. et al. (2004) J Mammary Gland Biol Neoplasia 9, 109-18. 9 . Yang, X.R. et al. (2009) Nat Genet 41, 1176-8. 10 . Ho, I.C. and Glimcher, L.H. (2002) Cell 109 Suppl, S109-20. 11 . Peng, S.L. (2006) Cell Mol Immunol 3, 87-95. |
Western analysis of extracts from TALL-104 cells using TBX21 (V365) Antibody.Western免疫印迹。用TBX21 (V365) Antibody研究 TALL-104细胞的细胞提取液。 |