| 货号 | 2312S |
| 反应种属 | Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Synapsin Antibody detects endogenous levels of total synapsin protein. This antibody is expected to recognize all synapsin isoforms. |
| 使用方法 | WB(1:1000) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Synapsins, a group of at least five related members (synapsins Ia, Ib, IIa, IIb, and IIIa), are abundant brain proteins essential for regulating neurotransmitter release (1,2). All synapsins contain a short amino-terminal domain that is highly conserved and phosphorylated by PKA or CaM kinase I (1). Phosphorylation of the synapsin amino-terminal domain at Ser9 inhibits its binding to phospholipids and dissociates synapsins from synaptic vesicles (2). |
| 存放说明 | -20C |
| 计算分子量 | 77 in mouse brain homogenate. |
| 参考文献 | 1 . Greengard, P. (1987) Mol Neurobiol 1, 81-119. 2 . Hosaka, M. et al. (1999) Neuron 24, 377-87. |
Western blot analysis of mouse brain homogenates, untreated or phosphatase-treated, using Phospho-Synapsin (Ser9) Antibody #2311 (upper) or Synapsin Antibody (lower). Western blot分析小鼠大脑匀浆，未处理或磷酸酶处理，使用的抗体是Phospho-Synapsin (Ser9) Antibody 兔多抗#2311（上图）或Synapsin Antibody 兔多抗（下图）进行。 |
