| 货号 | 4100S |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | SNARK/NUAK2 Antibody detects endogenous levels of total SNARK/NUAK2 protein. |
| 使用方法 | WB(1:1000) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | SNARK was identified as an SNF1/AMPK-related kinase and member of the AMPK catalytic subunit family (1,2). This enzyme was separately identified as a TNFα-induced SNF1-like kinase 2 (NUAK2) (3). The kinase activity of SNARK/NUAK2 is increased by AMP and AICAR (1). SNARK/NUAK2 activity is regulated by a variety of cellular stresses such as endoplasmic reticulum (ER) stress and oxidative stresses (4), suggesting that SNARK/NUAK2 is a signaling molecule involved in the cell stress response (4). |
| 存放说明 | -20C |
| 计算分子量 | 70 |
| 参考文献 | 1 . Lefebvre, D.L. et al. (2001) Biochem J 355, 297-305. 2 . Suzuki, A. et al. (2003) Biochem Biophys Res Commun 311, 156-61. 3 . Yamamoto, H. et al. (2008) Biochem Biophys Res Commun 365, 541-7. 4 . Lefebvre, D.L. and Rosen, C.F. (2005) Biochim Biophys Acta 1724, 71-85. |
Western blot analysis of extracts from the mouse tibialis anterior (TA) muscle using SNARK/NUAK2 Antibody. western blot检测小鼠胫前肌提取物，所用抗体为SNARK/NUAK2 Antibody |
