货号 | 8442S |
反应种属 | Human/Mouse |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | SLC1A4 Antibody recognizes endogenous levels of total SLC1A4 protein. |
使用方法 | WB(1:1000) |
供应商 | CST |
灵敏度 | Endogenous |
背景 | SLC1A4, also known as ASCT1, is a neutral amino acid transporter. Its other name, ASCT1, was given because it mediates obligatory exchange of alanine, serine, cysteine, and threonine (1). SLC1A4 mediates the efflux of glutamate from the neuron into the synaptic junction via calcium-independent release, as well as mediating the efflux of L-serine from glial cells and its uptake by neurons (2). SLC1A4-mediated transport is shown to involve a symmetrical potassium-independent electroneutral exchange of neutral amino acids and sodium, such that the current activated during transport is carried only by chloride ions (3). |
存放说明 | -20C |
计算分子量 | 60-80 |
参考文献 | 1 . Takasaki, C. et al. (2007) Biomed Res 28, 61-9. 2 . Deng, X. et al. (2008) BMC Psychiatry 8, 58. 3 . Zerangue, N. and Kavanaugh, M.P. (1996) J Biol Chem 271, 27991-4. |
Western blot analysis of extracts from mouse brain and human cerebellum using SLC1A4 Antibody. Western blot分析小鼠大脑和人小脑提取物,使用的抗体是SLC1A4 Antibody 兔多抗。 |