货号 | 2065S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | Ribosomal Protein L26 Antibody detects endogenous levels of total ribosomal protein L26. |
使用方法 | WB(1:1000) |
供应商 | CST |
灵敏度 | Endogenous |
背景 | Ribosomal protein L26 (RPL26) is a component of the 60S ribosomal subunit and is involved in translation (1,2). It was shown that RPL26 increases the translation of p53 mRNA by binding to its 5 untranslated region (UTR) after DNA damage. Studies found that overexpression of RPL26 enhances the binding of p53 mRNA to the ribosomes and increases p53 translation. Overexpression of RPL26 also induces cell-cycle arrest at G1 phase and increases radiation-stimulated apoptosis (2). |
存放说明 | -20C |
计算分子量 | 17 |
参考文献 | 1 . Odintsova, T.I. et al. (2003) J Protein Chem 22, 249-58. 2 . Takagi, M. et al. (2005) Cell 123, 49-63. |
Western blot analysis of extracts from various cell types using Ribosomal Protein L26 Antibody. 使用Ribosomal Protein L26 Antibody,免疫印迹(Western Blot)分析在不同细胞系中Ribosomal Protein L26蛋白水平。 |