| 货号 | 2516S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | REDD1 Antibody detects transfected levels of REDD1 protein. |
| 使用方法 | WB(1:1000) |
| 供应商 | CST |
| 灵敏度 | Transfected Only |
| 背景 | REDD1 (REgulated in Development and DNA damage responses) expression is induced by hypoxia, cell stress, apoptosis and DNA damage. REDD1 is a transcriptional target of p53 and p63 following DNA damage, and links p63 to Ros (1). REDD1 functions as a negative regulator of mTOR in response to hypoxia in a tuberin-dependent manner (2). Depending on cell context, REDD1 can either be protecting or detrimental for cells under oxidative or ischemic stresses (3). |
| 存放说明 | -20C |
| 计算分子量 | 28 |
| 参考文献 | 1 . Ellisen, L.W. et al. (2002) Mol Cell 10, 995-1005. 2 . Brugarolas, J. et al. (2004) Genes Dev 18, 2893-904. 3 . Shoshani, T. et al. (2002) Mol Cell Biol 22, 2283-93. |
Western blot analysis of extracts from COS-7 cells, transfected with HA-REDD1 or untransfected (mock), using REDD1 Antibody. Western blot检测分析HA-REDD1转染或者未处理（mock）的COS-7细胞提取物，使用抗体是REDD1 抗体。 |
