| 货号 | 5657S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IF-IC |
| 目标/特异性 | RAIG1 Antibody recognizes endogenous levels of total RAIG1 protein. |
| 使用方法 | WB(1:1000) IF-IC (1:200) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Retinoic Acid-Induced Gene 1 (RAIG1), also called RAI3 and GPRC5A, belongs to the family of G protein-coupled receptors (GPCRs). GPCRs are the largest and most abundant receptor family in mammals, composed of more than one thousand members (1). Retinoic Acids (RA) are a group of pleiotropic signaling molecules that regulate a broad range of physiologic and developmental processes. It is thought that RAIG1 may be a downstream target of RA signaling (2). RAIG1 is expressed in lung tissue and in several lung cancer cell lines, and encodes a seven-transmembrane glycoprotein presumed to be a lung tumor suppressor gene (3,4). |
| 存放说明 | -20C |
| 计算分子量 | 40-50 |
| 参考文献 | 1 . Jörissen, H. et al. (2009) BMC Cancer 9, 200. 2 . Xu, J. et al. (2005) Am J Respir Cell Mol Biol 32, 381-7. 3 . Veling, G. et al. (1992) Kinderkrankenschwester 11, 118-20. 4 . Ye, X. et al. (2009) Cancer Biol Ther 8, 951-62. |
Confocal immunofluorescent analysis of MKN-45 (left) and 293 (right) cells using RAIG1 Antibody (green). Actin filaments have been labeled with DY-554 phalloidin. Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).使用RAIG1抗体对MKN-45（左）和293细胞（右）进行激光共聚焦荧光分析。使用DY-554鬼笔环肽（红色）标记肌动蛋白丝。蓝色假色=DRAQ5® #4084 (荧光DNA染料). | |
Western blot analysis of extracts from untransfected or human RAIG1-transfected 293T cells and untransfected MKN-45 cells using RAIG1 Antibody.未转染的293T细胞或经人RAIG1转染后的293T细胞和未经转染的MKN-45细胞使用RAIG1抗体进行western blot实验。 |
