货号 | 2167S |
反应种属 | Human/Mouse/Rat/Hamster/Monkey |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | Rab4 Antibody detects endogenous levels of total Rab4 protein. |
使用方法 | WB(1:1000) |
供应商 | CST |
灵敏度 | Endogenous |
背景 | Rab4 is a member of the Ras superfamily of small Rab GTPases implicated in endocytosis. Rab4 is localized at early endosomes/recycling endosomes and functions as a key regulator for sorting/recycling of membrane and proteins (1,2). Rab4 has two isoforms, Rab4A and Rab4B, both of which are localized in similar cellular compartments and are believed to have similar functions (4). Rab4 interacts with several Rab4 effectors in a complex on a special endosome site that promotes membrane/protein recycling (1,3). |
存放说明 | -20C |
计算分子量 | 25 |
参考文献 | 1 . Zerial, M. and McBride, H. (2001) Nat Rev Mol Cell Biol 2, 107-17. 2 . van der Sluijs, P. et al. (1992) Cell 70, 729-40. 3 . Deneka, M. et al. (2003) EMBO J 22, 2645-57. 4 . Krawczyk, M. et al. (2007) Nucleic Acids Res 35, 595-605. |
Western blot analysis of extracts from various cell types using Rab4 Antibody. 对多个细胞系使用Rab4 Antibody进行Western blot分析。 |