| 货号 | 3292S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | Pyk2 Antibody detects endogenous levels of total Pyk2 protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Protein tyrosine kinase Pyk2, also called CAKβ, RAFTK and CADTK, is a nonreceptor tyrosine kinase structurally related to focal adhesion kinase (FAK) (1-4). Pyk2 is predominantly expressed in cells derived from hematopoietic lineages and in the central nervous system. Pyk2 is one of the signaling mediators for the G-protein-coupled receptors and MAP kinase signaling pathway. It plays an important role in cell spreading and migration (5-7). |
| 存放说明 | -20C |
| 计算分子量 | 116 |
| 参考文献 | 1 . Avraham, S. et al. (1995) J. Biol. Chem. 270, 27742-27751. 2 . Lev, S. et al. (1995) Nature 376, 737-745. 3 . Sasaki, H. et al. (1995) J. Biol. Chem. 270, 21206-21219. 4 . Yu, H. et al. (1996) J. Biol. Chem. 271, 29993-29998. 5 . Duong, L.T. et al. (2001) J Biol Chem 276, 7484-92. 6 . Watson, J.M. et al. (2001) J Biol Chem 276, 3536-42. 7 . Tang, H. et al. (2002) J Biol Chem 277, 5441-7. |
Western blot analysis of extracts from SKW6.4 (lane 1), Jurkat (lane 2), Namalwa (lane 3) and LS 102.9 (lane 4) cells using Pyk2 Antibody.Western blot方法检测细胞提取物：SKW6.4 (1号条带), Jurkat (2号条带), Namalwa (3号条带) and LS 102.9 (4号条带)细胞。使用的抗体是Pyk2 Antibody。 |
