| 货号 | 12323S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | Pumilio 2 Antibody recognizes endogenous levels of total Pumilio 2 protein. Pumilio 2 Antibody is expected to recognize all three known Pumilio 2 protein isoforms. Cross reactive bands of unknown origin are observed around 45 kDa. |
| 使用方法 | WB(1:1000) IP (1:100) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Pumilio 1 and Pumilio 2 (PUM1, PUM2, or Pumilio homolog 1 and 2, respectively) are evolutionarily conserved RNA binding proteins that are thought to repress translation and stability of mRNA targets by binding to the 3-UTR of specific RNA sequences (1). Pumilio proteins have been implicated in the regulation of genes involved in embryogenesis and germline cell development (2). Research studies have shown that PUM2 may have a role in neural stem cell fate decisions (3). |
| 存放说明 | -20C |
| 计算分子量 | 110-125 |
| 参考文献 | 1 . Weidmann, C.A. and Goldstrohm, A.C. (2012) Mol Cell Biol 32, 527-40. 2 . Spassov, D.S. and Jurecic, R. (2003) IUBMB Life 55, 359-66. 3 . Vessey, J.P. et al. (2012) Cell Stem Cell , . |
Western blot analysis of extracts from A172 and NTERA-2 cl.D1 cells using Pumilio 2 Antibody. Western blot方法检测A172 和 NTERA-2 cl.D1细胞的提取物，使用的抗体为Pumilio 2 Antibody。 |
