PHGDH Antibody
货号：
13428S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 13428S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | PHGDH Antibody recognizes endogenous levels of total PHGDH protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Research studies demonstrate that an increase in serine biosynthesis supports growth and proliferation of cancer cells (2-4), which is supported by amplification and overexpression of PHGDH in a subset of melanoma and breast cancers (5,6). Suppression of PHGDH expression in cell lines with elevated PHGDH levels causes a strong decrease in cell proliferation and inhibits tumor growth in vivo (5). Additional evidence suggests that PHGDH interacts with and stabilizes FoxM1, which promotes the proliferation, invasion, and tumorigenicity of glioma cells (7). |
| 存放说明 | -20C |
| 计算分子量 | 57 |
参考图片Western blot analysis of extracts from 293, HeLa, and NIH/3T3 cells using PHGDH Antibody. 使用PHGDH Antibody对293，HeLa和NIH/3T3细胞提取物进行western blot分析。 |
