| 货号 | 8144S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | PDLIM2 Antibody recognizes endogenous levels of total PDLIM2 protein. |
| 使用方法 | WB(1:1000) |
| 供应商 | CST |
| 背景 | PDLIM2, also known as Mystique, contains an amino-terminal PDZ domain and a carboxy-terminal LIM domain. PDLIM2 was orginally found to be associated with cytoskeletal proteins in epithelial cells to promote cell attachment and migration (1,2). Subsequent studies have shown that PDLIM2 can also inhibit NF-κB activity by acting as a nuclear ubiquitin E3 ligase for p65 (3). PDLIM2 is suppressed in cancer cell lines by DNA methylation (4,5). Expression of PDLIM2 can inhibit anchorage-independent growth and tumor formation. |
| 存放说明 | -20C |
| 计算分子量 | 38 |
Western blot analysis of extracts from various cell lines and mouse lung using PDLIM2 Antibody. 使用PDLIM2 Antibody，免疫印迹（Western Blot）分析不同细胞和小鼠肺组织中PDLIM2蛋白水平。 | |
Western blot anlysis of extracts from 293T cells, mock transfected (-) or transfected with a human PDLIM2 construct (hPDLIM2, +), using PDLIM2 Antibody. 使用PDLIM2 Antibody，免疫印迹（Western Blot）分析293T细胞中PDLIM2蛋白水平，细胞分为mock transfected (-)或transfected with a human PDLIM2 construct (hPDLIM2, +)。 |
