PDE5 Antibody
货号：
2395S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2395S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | PDE5 Antibody detects endogenous levels of total PDE5 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The superfamily of phosphodiesterases (PDEs) catalyses the hydrolysis of 3,5-cyclic nucleotides into the corresponding nucleotide 5-monophosphates. PDE5 is a cGMP-specific enzyme that contains two cGMP binding sites in its amino-terminal regulatory domain (1). Elevation of cGMP levels causes activation of PKG, which phosphorylates PDE5 at Ser102 (2). Phosphorylation of PDE5 stimulates its enzymatic activity and enhances cGMP binding affinity in the regulatory domain, leading to a decrease in intracellular cGMP levels (3,4). |
| 存放说明 | -20C |
| 计算分子量 | 100 |
参考图片Western blot analysis of extract from LN-18 cells, using PDE5 Antibody. 对LN-18细胞抽提液使用PDE5抗体进行Western blot分析。 |
