Paxillin Antibody
货号：
2542S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2542S |
| 反应种属 | Human/Mouse/Rat/Monkey/Bovine/Pig |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Paxillin Antibody detects endogenous levels of total paxillin protein. The antibody does not cross-react with related proteins. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Paxillin is a multi-domain protein that localizes primarily to focal adhesion sites to the extracellular matrix (1). Paxillin is one of the key components of integrin signaling and tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal reorganization (2). Paxillin is phosphorylated by another focal adhesion component, focal adhesion kinase (FAK), at Tyr118 (3,4). Phospho-Tyr118 may provide a docking site for recruitment of other signaling molecules to focal adhesions. It has been shown that the SH2 domain of Crk binds to the phosphorylated Tyr118 of paxillin (5). |
| 存放说明 | -20C |
| 计算分子量 | 68 |
参考图片Western blot analysis of extracts from various cell lines, using Paxillin Antibody.使用Paxillin抗体对多种细胞提取物进行western blot分析。 |
