PARN (A42) Antibody
货号：
3894S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3894S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | PARN (A42) Antibody detects endogenous levels of total PARN protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Cellular levels of mRNAs are controlled by mRNA stability, the rate of synthesis and the rate of degradation. The presence and length of the poly(A) tail has been associated with mRNA stability (1). Exonucleolytic shortening of the poly(A) tail is the process that initiates the decay of many eukaryotic mRNAs (2). Poly(A)-specific ribonuclease (PARN) is the enzyme responsible for initiation of deadenylation and exonucleolytic shortening of mRNA transcripts. Through an evolutionarily conserved mechanism, PARN also translationally silences selective mRNAs during early embryonic development (3). PARN is constitutively expressed in most mammalian tissues and plays a critical role in the post-transcriptional control of gene expression (4). |
| 存放说明 | -20C |
| 计算分子量 | 78 |
参考图片Western blot analysis of extracts from various cell lines using PARN (A42) Antibody. 使用PARN (A42) Antibody，免疫印迹（Western blot）分析不同细胞系的裂解物。 |
