NPL4 Antibody
货号：
13489S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 13489S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | NPL4 Antibody recognizes endogenous levels of total NPL4 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Nuclear protein localization protein 4 (NPL4, NPLOC4) was originally identified as a yeast nuclear transport protein that was later recognized as a critical component of the endoplasmic reticulum-associated degradation (ERAD) pathway (1,2). Mammalian NPL4 protein has an amino-terminal ubiquitin-like domain containing a p97 binding site, and a conserved carboxy-terminal zinc finger (NZF) motif responsible for binding ubiquitinated target proteins (2,3). NPL4 binds ubiquitin fusion degradation protein 1 (UFD1) to form a heterodimer that associates with the p97 AAA-ATPase, creating a protein complex that mediates delivery of ubiquitinated ER proteins to the proteasome (4,5). |
| 存放说明 | -20C |
| 计算分子量 | 68, 71 |
参考图片Western blot analysis of extracts from various cell lines using NPL4 Antibody.Western blot检测多种细胞提取物，使用的抗体是NPL4 Antibody. |
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing Myc/DDK-tagged full-length human NPL4 protein (hNPL4-Myc/DDK; +), using NPL4 Antibody.Western blot分析293T细胞提取物，对照未转染（-）或转染了Myc/DDK标签的全长人源的NPL4蛋白(hNPL4-Myc/DDK; +)，使用的抗体是NPL4 Antibody。 |
