| 货号 | 5058S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | NPC1L1 Antibody detects endogenous levels of total NPC1L1 protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | Niemann-Pick C1-like 1 (NPC1L1) is a transmembrane protein that plays a critical role in cholesterol absorption (1). It is highly expressed in small intestine and localized along the brush border in both human and mouse epithelial cells (2,3). NPC1L1 mediates cholesterol uptake via vesicular endocytosis (4). Ezetimibe, a potent cholesterol absorption inhibitor used to treat hypercholesterolemia (5), inhibits cholesterol uptake by preventing NPC1L1 from incorporating into clathrin-coated vesicles (4). |
| 存放说明 | -20C |
| 计算分子量 | 140 |
Western blot analysis of extracts from Hep G2 and MKN-45 cells using NPC1L1 Antibody. western blot 检测Hep G2 和MKN-45 细胞提取物，所用抗体为NPC1L1 Antibody |
