nNOS Antibody
货号：
4234S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 4234S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | nNOS Antibody detects endogenous levels of total nNOS protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Nitric Oxide Synthase (NOS) catalyses the formation of nitric oxide (NO) and citruline from L-arginine, oxygen and cofactors. Three family members have been characterized: neuronal NOS (nNOS), which is found primarily in neuronal tissue; inducible NOS (iNOS), which is induced by interferon gamma and lipopolysaccharides in the kidney and cardiovascular system; and endothelial NOS (eNOS), which is expressed in blood vessels (1). NO is a messenger molecule with diverse functions throughout the body including the maintenance of vascular integrity, homeostasis, synaptic plasticity, long-term potentiation, learning, and memory (2,3).nNOS binds selectively to the second PDZ domain of PSD-95, and the enzymatic activity of nNOS is either downregulated by phosphorylation at Ser847 by CaM-KII or stimulated by calcium influxes governed by the NMDA receptor channels (4-5). |
| 存放说明 | -20C |
| 计算分子量 | 160 |
参考图片Western blot analysis of extracts from mouse and rat brain, using nNOS Antibody. Western blot分析小鼠和大鼠大脑提取物，使用的抗体是nNOS Antibody 兔多抗。 |
