NKX2.2 Antibody
货号：
12310S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 12310S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | NKX2.2 Antibody recognizes transfected levels of total NKX2.2 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The NKX family of homeobox genes are known to act as intermediaries in the neural response to Sonic hedgehog signaling during central nervous system development (1). NKX2.2 is a member of this family of transcription factors and is necessary for neuroendocrine differentiation in the central nervous system and pancreas (2,3). NKX2.2 mutant mice die shortly after birth due to incomplete differentiation of insulin-producing pancreatic β cells and defects in ventral neural patterning (2,3). According to the research literature, expression of NKX2.2 has also been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors (4). |
| 存放说明 | -20C |
| 计算分子量 | 40 |
参考图片Western blot analysis of extracts from 293 cells, mock transfected (-) or transfected with a construct expressing Myc/DDK-tagged full-length human NKX2.2 (hNKX2.2-Myc/DDK; +), using NKX2.2 Antibody (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). 空载体转染对照（-）或转染了表达含有Myc/DDK标签的全长人NKX2.2质粒（hNKX2.2-Myc/DDK; +）的293细胞提取物，使用NKX2.2抗体（上）或β-Actin (D6A8) Rabbit mAb 兔单抗#8457（下）进行western blot分析。 |
