Nicastrin Antibody
货号：
3632S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3632S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Nicastrin Antibody detects endogenous levels of Nicastrin. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Nicastrin is a transmembrane glycoprotein serving as an essential component of the γ-secretase complex (1,2). Nicastrin is physically associated with presenilin and plays an important role in the stabilization and correct localization of presenilin to the membrane-bound γ-secretase complex (3). Nicastrin also serves as a docking site for γ-secretase substrates such as APP and Notch, directly binding to them and properly presenting them to γ-secretase to ensure the correct cleavage process (2,4). |
| 存放说明 | -20C |
| 计算分子量 | 110, 120 |
参考图片Western blot analysis of extracts from human (HeLa and SK-N-MC; lanes 1 and 2), monkey (COS; lane 3), mouse (Neuro 2A and L; lanes 4 and 5) and rat (PC12 and C6; lanes 6 and 7) cell lines, using Nicastrin Antibody. Western blot分析人HeLa和SK-N-MC细胞（第1和2列）、猴COS细胞 ( lane 3)、小鼠Neuro 2A和L细胞（第4和5列）和大鼠PC12和C6细胞（第6和7列）提取物，使用的抗体是Nicastrin Antibody 兔多抗。 |
