NGF Antibody
货号：
2046S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2046S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | NGF Antibody detects recombinant NGF protein. It does not cross-react with other proteins. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Nerve growth factor (NGF) is a small, secreted protein and member of the neurotrophin family of growth factors that promote neuronal cell survival and differentiation (1). Producing cells release NGF that bind and activate TrkA high affinity receptors to mediate NGF-driven signaling. NGF also binds to a low affinity p75 (NTR) receptors, which belong to the death receptor family (2). Although NGF has been classically described as favoring neuron survival and differentiation, nerve growth factor can promote apoptosis in cells that contain p75 (NTR) and lack TrkA. NGF can induce neuron death in a variety of neurodegenerative conditions, including Alzheimer disease (3). Besides its neurotrophic actions, NGF has an effect on non-neuronal cells and may help mediate inflammation, angiogenesis, and stimulate breast cancer cell growth (4-6). NGF signaling is looking increasingly promising as potential drug targets for diseases. |
| 存放说明 | -20C |
| 计算分子量 | 13 |
参考图片Western blot analysis of various concentrations of recombinant human NGF protein using NGF Antibody. Western blot分析不同浓度的重组人NGF蛋白，使用的抗体是NGF Antibody 兔多抗。 |
