货号 | 2154S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit |
应用 | W/IF-F |
目标/特异性 | Musashi Antibody detects endogenous levels of total Musashi 1 and 2 protein. |
使用方法 | WB(1:1000) IF-F (1:25) |
供应商 | CST |
背景 | Musashi-1 and Musashi-2 are RNA-binding proteins which play a role in asymmetric cell division of ectodermal precursor cells by regulating the translation of target mRNA. Both family members augment Notch signaling and repress the translation of m-Numb, a protein that positively modulates differentiation of neural stem cells into neurons. Thus, Musashi contributes to the maintenance of neural stem cells (1). While Musashi-1 is frequently used as a marker for proliferating neural precursor cells, it is also expressed in epithelial stem cells including intestinal and mammary gland stem cells (2-4). |
存放说明 | -20C |
计算分子量 | 35 |
Western blot analysis of extracts from IEC-6 and LS174T cells, using Musashi Antibody. Western blot分析IEC-6和LS174T细胞提取物,使用的抗体是Musashi Antibody 兔多抗。 | |
Confocal immunofluorescence images of the subventricular zone of rat striatal sections labeled with Musashi Antibody (red) and Phospho-S6 Ribosomal Protein (Ser235/236) (2F9) Rabbit mAb (Alexa Fluor® 488 Conjugate) #4854 (green). Proliferating/mitotic cells are labeled with Phospho-Histone H3 (Ser10) (6G3) Mouse mAb #9706 (blue). 共聚焦免疫荧光分析大鼠脑室下纹状体区域,使用Musashi Antibody 兔多抗(红色)和Phospho-S6 Ribosomal Protein (Ser235/236) (2F9) Rabbit mAb (Alexa Fluor® 488 Conjugate) #4854(绿色)进行标记。增生/分裂细胞用 Phospho-Histone H3 (Ser10) (6G3) Mouse mAb 兔单抗#9706(蓝色)标记。 |