MCP-1 Antibody (Mouse Specific)
货号:
2029S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 2029S |
反应种属 | Mouse |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | MCP-1 Antibody (Mouse Specific) detects endogenous levels of total mouse MCP-1 protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Monocyte chemotactic protein-1 (MCP-1), also known as CCL2, monocyte chemotactic activating factor (MCAF) or glioma-derived chemotactic factor-2 (GDCF-2), is the product of the human JE gene and a member of the family of C-C (or β) chemokines (1-4). The predicted molecular weight of MCP-1 protein is 11-13 kDa, but it may migrate at 20-30 kDa due to glycosylation. MCP-1 is secreted by a variety of cell types in response to pro-inflammatory stimuli and was originally described for its chemotactic activity on monocytes. This activity has led to studies demonstrating its role in diseases characterized by monocyte infiltrates such as psoriasis (5), rheumatoid arthritis (6) and atherosclerosis (7). MCP-1 may also contribute to tumor progression and angiogenesis (8). Signaling by MCP-1 is mediated by the G-protein coupled receptor CCR2 (9). |
存放说明 | -20C |
计算分子量 | 11-13, 20-30 |
参考图片Western blot analysis of extracts from the media of RAW 264.7 cells, untreated or treated with LPS (1 μg/ml, overnight), using MCP-1 Antibody (Mouse Specific).Western免疫印迹。用MCP-1 Antibody (Mouse Specific)研究未经处理的和经LPS (1 μg/ml, 过夜)处理的RAW 264.7 细胞培养基的提取液。 |
Western blot analysis of recombinant mouse MCP-1 protein using MCP-1 Antibody (Mouse Specific).Western免疫印迹。用MCP-1 Antibody (Mouse Specific)研究重组鼠MCP-1蛋白。 |