MCP-1 Antibody
货号：
2027S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2027S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | MCP-1 Antibody detects endogenous levels of total human MCP-1 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Monocyte chemotactic protein-1 (MCP-1), also known as CCL2, monocyte chemotactic activating factor (MCAF) or glioma-derived chemotactic factor-2 (GDCF-2), is the product of the human JE gene and a member of the family of C-C (or β) chemokines (1-4). The predicted molecular weight of MCP-1 protein is 11-13 kDa, but it may migrate at 20-30 kDa due to glycosylation. MCP-1 is secreted by a variety of cell types in response to pro-inflammatory stimuli and was originally described for its chemotactic activity on monocytes. This activity has led to studies demonstrating its role in diseases characterized by monocyte infiltrates such as psoriasis (5), rheumatoid arthritis (6) and atherosclerosis (7). MCP-1 may also contribute to tumor progression and angiogenesis (8). Signaling by MCP-1 is mediated by the G-protein coupled receptor CCR2 (9). |
| 存放说明 | -20C |
| 计算分子量 | 13-15 |
参考图片Western blot analysis of extracts from the media of A549 cells, untreated or treated with TNF-α #2169 (20 ng/ml, 6 hrs.), using MCP-1 Antibody.Western免疫印迹。用MCP-1 Antibody研究未经处理的和经TNF-α #2169 (20 ng/ml, 6 hrs)处理的A549细胞的培养基提取液。 |
Western blot analysis of extracts from HeLa cells, mock transfected or transfected with human MCP-1, using MCP-1 Antibody.Western免疫印迹。用MCP-1 Antibody研究未转染和转染了人MCP-1的HeLa细胞的细胞提取液。 |
