LDHA Antibody
货号：
2012S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2012S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | LDHA Antibody detects endogenous levels of total LDHA protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Lactate dehydrogenase (LDH) catalyzes the interconversion of pyruvate and NADH to lactate and NAD+. When the oxygen supply is too low for mitochondrial ATP production, this reaction recycles NADH generated in glycolysis to NAD+, which reenters glycolysis. The major form of LDH found in muscle cells is the A (LDHA) isozyme. The LDHA promoter contains HIF-1-α binding sites (1). LDHA expression is induced under hypoxic conditions (2). During intensive and prolonged muscle exercise, lactate accumulates in muscle cells when the supply of oxygen does not meet demand. When oxygen levels return to normal, LDH converts lactate to pyruvate to generate ATP in the mitochondrial electron transport chain. |
| 存放说明 | -20C |
| 计算分子量 | 37 |
参考图片Western blot analysis of extracts from various cell lines using LDHA Antibody. 对多个细胞系抽提液使用LDHA Antibody进行Western blot分析。 |
