| 货号 | 2081S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | La Antigen Antibody detects endogenous levels of total La Antigen protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | La antigen is recognized by antibodies in patients with autoimmune disorders such as systemic lupus erythematosus and Sjögrens syndrome (1). La antigen binds to the 5-noncoding region of poliovirus RNA and is an IRES trans-acting factor (1,2). Depletion of La antigen reduces the function of poliovirus IRES in vivo (3). La antigen, when phosphorylated at Ser366, has been shown to associate with nuclear precursor tRNAs and facilitate their processing (4). The nonphosphorylated La antigen interacts with the mRNAs that have 5-terminal oligopyrimidine (5TOP) motifs to control protein synthesis (4). |
| 存放说明 | -20C |
| 计算分子量 | 50 |
Western blot analysis of extracts from various cell types using La Antigen Antibody. 使用La Antigen Antibody，免疫印迹（Western blot）分析不同细胞系的提取物。 |
