| 货号 | 4898S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IF-IC |
| 目标/特异性 | Keratin 7 (R458) Antibody detects endogenous levels of total keratin 7 protein. |
| 使用方法 | WB(1:1000) IF-IC (1:50) |
| 供应商 | CST |
| 背景 | Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as biomarkers (1). Mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6). |
| 存放说明 | -20C |
| 计算分子量 | 55 |
Western blot analysis of extracts from HeLa and A549 cells using Keratin 7 (R458) Antibody.使用Keratin 7 (R458) Antibody，免疫印迹（Western Blot）分析HeLa和A549细胞中Keratin 7蛋白水平。 | |
Confocal immunofluorescent analysis of HeLa (left) and MCF7 (right) cells using Keratin 7 (R458) Antibody (green). Actin filaments have been labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).使用Keratin 7 (R458) Antibody (绿色)标记，共聚焦免疫荧光观察Keratin 7蛋白在HeLa(左图)和MCF7 (右图)细胞中定位。DY-554 phalloidin标记微丝蛋白（红色）。蓝色= DRAQ5®#4084(DNA荧光染料)。 |
