| 货号 | 3746S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IF-IC |
| 使用方法 | WB(1:1000) IP (1:50) IF-IC (1:25) |
| 供应商 | CST |
| 背景 | JunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals (1-4). While JunB sometimes antagonizes c-Jun transcriptional activity, it may functionally substitute for c-Jun during development in mice (5-7). JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML) (8,9). |
| 存放说明 | -20C |
| 计算分子量 | 42, 43 |
Confocal immunofluorescent analysis of HeLa cells using JunB (G53) Antibody (green). Actin filaments have been labeled with Alexa Fluor® 555 phalloidin (red).激光共聚焦荧光法检测HeLa 细胞，标记的抗体是JunB (G53) Antibody(绿色)。肌动蛋白丝用Alexa Fluor® 555 鬼笔环肽(红色)标记。 | |
Western blot analysis of total cell lysates from HeLa, MCF-7 and SW620 cells using JunB (G53) Antibody.Western blot 检测总细胞提取物：HeLa, MCF-7和SW620细胞，使用的抗体是JunB (G53) Antibody。 |
