IκB-ζ Antibody (Mouse Specific)
货号：
93726S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 93726S |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The NF-κB/Rel transcription factors are present in the cytosol in an inactive state complexed with the inhibitory IκB proteins (1-3). Activation occurs via phosphorylation of IκBα at Ser32 and Ser36 followed by proteasome-mediated degradation that results in the release and nuclear translocation of active NF-κB (3-7). IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. Kinases that phosphorylate IκB at these activating sites have been identified (8). |
| 存放说明 | -20C |
| 计算分子量 | 75, 85 |
参考图片Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing full-length mouse IκB-ζ (mIκB-ζ; +) using IκB-ζ Antibody (Mouse Specific). |
Western blot analysis of extracts from Raw 264.7 and J774A.1 cell lines, untreated (-) or treated with LPS (1 μg/ml, 4 hr; +) using IκB-ζ Antibody (Mouse Specific) (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). |
