| 货号 | 4920S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | IRF-7 Antibody detects endogenous levels of IRF-7 protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | Interferon regulatory factors (IRFs) comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection (1). IRFs play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. The IRF family includes nine members: IRF-1, IRF-2, ISGF3γ/p48, IRF-3, IRF-4 (Pip/LSIRF/ICSAT), IRF-5, IRF-6, IRF-7, and IRF-8/ICSBP. All IRF proteins share homology in their amino-terminal DNA-binding domains. IRF family members regulate transcription through interactions with proteins that share similar DNA-binding motifs, such as IFN-stimulated response elements (ISRE), IFN consensus sequences (ICS) and IFN regulatory elements (IRF-E) (2). |
| 存放说明 | -20C |
| 计算分子量 | 65 |
Western blot analysis of extracts from Jurkat cells treated with IFN-α (100 nM) for the indicated times, using IRF-7 Antibody.Western免疫印迹。用IRF-7 Antibody研究经IFN-α (100 nM)处理一定时间的Jurkat细胞的细胞提取液。 | |
Western blot analysis of extracts from DLD-1 cells, untreated or treated overnight with IFN-α (100 nM), using IRF-7 Antibody.Western免疫印迹。用IRF-7 Antibody研究未经处理的和经IFN-α (100 nM)处理过夜的DLD-1细胞的细胞提取液。 |
