IRF-6 Antibody
货号：
6948S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 6948S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | IRF-6 Antibody recognizes endogenous levels of total IRF-6 protein. |
| 使用方法 | WB(1:1000)
IP (1:100) |
性能| 供应商 | CST |
| 背景 | Interferon regulatory factors (IRFs) comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection (1). IRFs play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. The IRF family includes nine members: IRF-1, IRF-2, ISGF3γ/p48, IRF-3, IRF-4 (Pip/LSIRF/ICSAT), IRF-5, IRF-6, IRF-7, and IRF-8/ICSBP. All IRF proteins share homology in their amino-terminal DNA-binding domains. IRF family members regulate transcription through interactions with proteins that share similar DNA-binding motifs, such as IFN-stimulated response elements (ISRE), IFN consensus sequences (ICS) and IFN regulatory elements (IRF-E) (2). |
| 存放说明 | -20C |
| 计算分子量 | 58, 60 |
参考图片Western blot analysis of extracts from various cell lines using IRF-6 Antibody. Absence of IRF-6 in MCF7 cells has been reported previously (5). Doublet has been reported to result from phosphorylation (6).Western免疫印迹。用IRF-6 Antibody研究各种细胞的细胞提取液。先前的报道IRF-6在MCF7细胞中缺失(5)。两条条带是由于磷酸化所致(6)。 |
