| 货号 | 4950S |
| 反应种属 | Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | IRF-5 Antibody (Rodent Specific) detects endogenous levels of total IRF-5 protein. |
| 使用方法 | WB(1:1000) IP (1:100) |
| 供应商 | CST |
| 背景 | Interferon regulatory factors (IRFs) comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection (1). IRFs play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. The IRF family includes nine members: IRF-1, IRF-2, ISGF3γ/p48, IRF-3, IRF-4 (Pip/LSIRF/ICSAT), IRF-5, IRF-6, IRF-7, and IRF-8/ICSBP. All IRF proteins share homology in their amino-terminal DNA-binding domains. IRF family members regulate transcription through interactions with proteins that share similar DNA-binding motifs, such as IFN-stimulated response elements (ISRE), IFN consensus sequences (ICS) and IFN regulatory elements (IRF-E) (2). |
| 存放说明 | -20C |
| 计算分子量 | 60 |
Western blot analysis of extracts from A20 and BaF3 cells using IRF-5 Antibody (Rodent Specific).Western免疫印迹。用IRF-5 Antibody (Rodent Specific)研究 A20 和BaF3细胞的细胞提取液。 | |
Western blot analysis of extracts from Raw264.7 cells, untreated or LPS-treated (1 µg/ml for 6 h), M12.4.1 cells and A20 cells, using IRF-5 Antibody (Rodent Specific).Western免疫印迹。用IRF-5 Antibody (Rodent Specific)研究未经处理的和经 LPS(1 µg/ml，6 h)处理的Raw264.7细胞，M12.4.1 细胞和A20细胞的细胞提取液。 |
