Integrin α6 Antibody
货号：
3750S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3750S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Integrin α6 Antibody detects endogenous levels of total integrin α6 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1,2). The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling) (1,2).
Integrin α6 is a 120 kDa protein with two splice variants, integrin α6, 6A and 6B (3), which function as receptors for laminins on the basal membrane to mediate cellular adhesion events (4-6). α6 integrins have been shown to play an important role in hematopoietic stem and progenitor cell homing to the bone marrow. |
| 存放说明 | -20C |
| 计算分子量 | 150, 125 |
参考图片Western blot analysis of extracts from various cell lines and tissues using Integrin α6 Antibody.使用Integrin α6抗体对多种细胞和组织提取物进行western blot分析。 |
