Integrin α5 Antibody
货号:
4705S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 4705S |
反应种属 | Human/Mouse/Monkey |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | Integrin α5 Antibody detects endogenous levels of total integrin α5 protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1,2). The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling) (1,2).
Integrin α5/β1 is involved in multiple biological processes including embryonic development, angiogenesis and tumor metastasis (4,5). By interaction with its fibronectin ligand, α5/β1 transduces signals that regulate cell adhesion, migration, matrix assembly and cytoskeletal organization (6). |
存放说明 | -20C |
计算分子量 | 150 |
参考图片Western blot analysis of extracts from A549, NIH/3T3 and COS cell lines using Integrin α5 Antibody.使用整合素α5抗体对 A549, NIH/3T3 和COS 细胞提取物进行western blot分析。 |