HSPB8/HSP22 Antibody
货号：
3059S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3059S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | HSPB8/HSP22 Antibody detects endogenous levels of total HSPB8/HSP22 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | HSPB8 (HSP22) is a member of the small heat shock protein superfamily and the human protein is most closely related to HSP27. Similar to most other small HSPs (sHSPs), HSPB8 is predominantly transcribed in skeletal muscle and heart (1). In a two hybrid screen, HSPB8 interacted preferentially with a triple aspartate form of HSP27 which mimics HSP27 phosphorylated at Ser15, Ser78, and Ser82, as compared to wild-type HSP27 (2). HSPB8 has two binding domains (N- and C-terminal) that are specific for different binding partners, and has the ability to bind to itself and other sHSPs such as HSPB7 and HSPB2 (3). The chaperone-like activity is of great importance to the function of HSP22 in various processes including proliferation, apoptosis and macroautophagy (4). |
| 存放说明 | -20C |
| 计算分子量 | 22 |
参考图片Western blot analysis of extracts from various cell lines using HSPB8/HSP22 Antibody. 对多个细胞系使用HSPB8/HSP22 Antibody进行Western blot分析。 |
