HELLS Antibody
货号：
7998S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 7998S |
| 反应种属 | Human/Mouse/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | HELLS Antibody recognizes endogenous levels of total HELLS protein. HELLS Antibody is predicted to detect multiple isoforms of this protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | HELLS, or LSH1, is a lymphoid-specific helicase thought to be involved in cellular proliferation and leukemogenesis (1,2). It is believed to be a chromatin remodeler and is required for DNMT1-mediated methylation maintenance and DNMT3A/DNMT3B-mediated de novo methylation. The role of HELLS in methylation maintenance was thought to be largely confined to repetitive DNA sequences, including major and minor satellite sequences, rather than single copy genes (3,4); recent evidence suggests a role in genome-wide cysteine methylation at non-repeat sequences (5). De novo methylation maintenance is associated with silencing of specific genes, some known to be involved in pluripotency and lineage commitment (6,7). |
| 存放说明 | -20C |
| 计算分子量 | 97 |
参考图片Western blot analysis of extracts from various cell lines using HELLS Antibody. 使用HELLS Antibody，免疫印迹(Western blot)分析不同细胞中HELLS的蛋白水平。 |
