Gα(i) Antibody
货号:
5290S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 5290S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | Gα(i) Antibody detects endogenous levels of total Gα(i) protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of α, β and γ subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli. To date, over 20 known Gα subunits have been classified into four families, Gα(s), Gα(i/o), Gα(q) and Gα(12), based on structural and functional similarities (1,2). Phosphorylation of Tyr356 of Gα(q)/Gα(11) is essential for activation of the G protein, since phenylalanine substitution for Tyr356 changes the interaction of Gα with receptors and abolishes ligand-induced IP3 formation (3). |
存放说明 | -20C |
计算分子量 | 40 |
参考图片Western blot analysis of extracts from various tissues using Gα(i) Antibody. 对多个细胞系使用Gα(i)抗体进行Western blot分析。 |