Gremlin Antibody
货号：
4383S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 4383S |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Gremlin Antibody detects transfected levels of total gremlin protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Gremlin is a secreted antagonist of bone morphogenetic proteins that play important roles during development. Gene targeting generates gremlin deficient mice that die shortly after birth due to absent kidneys and defects in lung septation (1-3). Gremlin also plays a role in cardiomyogenesis and angiogenesis (4,5). TGF-β can induce gremlin expression under pathological conditions. Gremlin colocalizes with TGF-β in tubulointerstitial fibrosis associated with chronic allograft nephropathy and is expressed in diabetic nephropathy in vivo (6-8). Gremlin is widely expressed in cancer associated stromal cells and can enhance cancer cell proliferation (9). |
| 存放说明 | -20C |
| 计算分子量 | 21 |
参考图片Western analysis of cell extracts from COS cells, untreated or transfected with a mouse Gremlin expression construct, using Gremlin Antibody.使用Gremlin抗体，对未经处理或转染了Gremlin表带载体的COS细胞提取物进行western分析。 |
