Granzyme A Antibody
货号：
4928S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 4928S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/E-P |
| 目标/特异性 | Granzyme A Antibody detects endogenous levels of Granzyme A protein. No cross-reactivity was observed with Granzyme B. |
| 使用方法 | WB(1:1000)
E-P (1:100) |
性能| 供应商 | CST |
| 背景 | Granzymes are a family of serine proteases expressed by cytotoxic T lymphocytes and natural killer (NK) cells and are key components of immune responses to pathogens and transformed cells (1). Granzymes are synthesized as zymogens and are processed into mature enzymes by cleavage of a leader sequence. They are released by exocytosis in lysosome-like granules containing perforin, a membrane pore-forming protein. Granzyme B has the strongest apoptotic activity of all the granzymes as a result of its caspase-like ability to cleave substrates at aspartic acid residues thereby activating procaspases directly and cleaving downstream caspase substrates (2,3). |
| 存放说明 | -20C |
| 计算分子量 | 28 |
参考图片 |
Western blot analysis of recombinant His-tagged Granzyme A (10 ng) and lysates from the natural killer cell line NK-92, using Granzyme A Antibody. |
