GCNF Antibody
货号:
5417S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 5417S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | GCNF Antibody detects endogenous levels of total GCNF protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | GCNF (Germ Cell Nuclear Factor), also known as NR6A1 (Nuclear Receptor Subfamily 6 Group A member), is an orphan member of the nuclear receptor gene superfamily (1). It has been shown to be expressed in the nervous system during development and during specific stages in maturing germ cells of the ovary and testis in the adult, and has probable roles in gametogenesis, neurogenesis, and normal embryonic development during gastrulation (1,2). Inactivation of GCNF in mouse results in abnormal posterior development, impaired midbrain development, insufficient closure of the neural tube, and eventual embryonic death (3). GCNF has been shown to be a repressor of OCT-4 and of the protamine genes (4,5) and plays a critical role in the control of gene expression during embryogenesis and spermatogenesis (2,6). |
存放说明 | -20C |
计算分子量 | 50 |
参考图片Western blot analysis of extracts from various cell lines using GCNF Antibody.用GCNF在western blot实验中检测多种细胞提取物。 |